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    Largest Study of Cancer WGS Data Uncovers Dozens of New Mutational Signatures
    • Apr 25

    Largest Study of Cancer WGS Data Uncovers Dozens of New Mutational Signatures

    In what is claimed to be the biggest study of its kind, scientists headed by a team at Cambridge University Hospitals (CUH) and the...
    Immunotherapy Gets Boost from Listeria Delivered Tetanus Toxoid, Shrinks Pancreatic Tumors in MiceM
    • Mar 28

    Immunotherapy Gets Boost from Listeria Delivered Tetanus Toxoid, Shrinks Pancreatic Tumors in MiceM

    Pancreatic cancer is one of the most challenging cancers to treat. Patients with pancreatic tumors have dismal survival rates, as most...
    IDT Biologika and Exothera Collaborate on Scaling Up Viral Vaccines
    • Mar 7

    IDT Biologika and Exothera Collaborate on Scaling Up Viral Vaccines

    IDT Biologika, a Germany-based CDMO specializing in vaccines, gene and immune therapy, and oncolytic viruses, and Exothera, a CDMO in...
    New SuperFi-Cas9 Increases Fidelity Without Sacrificing Speed
    • Mar 4

    New SuperFi-Cas9 Increases Fidelity Without Sacrificing Speed

    CRISPR–Cas9 has limitations. One of the most concerning, in regards to using genome editing for therapeutic applications for humans, is...
    mRNA Nanoparticles Restore p53 Function, Improve Immunotherapy Response
    • Feb 24

    mRNA Nanoparticles Restore p53 Function, Improve Immunotherapy Response

    Researchers at Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH) have used mRNA nanoparticles to reprogram the...
    Using RNA to Produce More Effective Biotherapeutic Antibodies
    • Nov 4, 2021

    Using RNA to Produce More Effective Biotherapeutic Antibodies

    The distribution of glycans on a monoclonal antibody impacts its function and half-life. Earlier this month, Masue Marbiah, PhD, a...
    AI Tool Eve Accurately Predicts Disease Relevance of Human Genetic Variants
    • Oct 29, 2021

    AI Tool Eve Accurately Predicts Disease Relevance of Human Genetic Variants

    Understanding how the wealth of genetic variation in the human genome impacts on disease could potentially transform healthcare, but...
    Mitochondrial May Potentially Be Improved by New Approach
    • Sep 1, 2021

    Mitochondrial May Potentially Be Improved by New Approach

    Mitochondrial DNA diseases are common neurological conditions caused by mutations in the mitochondrial genome or nuclear genes...
    CRISPR-Based Tech Could Revolutionize Antibody-Based Diagnostics
    • Aug 19, 2021

    CRISPR-Based Tech Could Revolutionize Antibody-Based Diagnostics

    Scientists have used an adaptation of the genome editing technology CRISPR to develop a new peptide display platform that can be used as...
    New Therapy Targets Aggressive Chemotherapy-Resistant Breast Cancer
    • Aug 5, 2021

    New Therapy Targets Aggressive Chemotherapy-Resistant Breast Cancer

    One of the hardest cancers to treat are tumors in the breast that do not express receptors for estrogen, progesterone, and human...
    Blood Pressure Drug Could Help to Thwart Lymph Node Tumors’ Evasive Tactics
    • Jul 21, 2021

    Blood Pressure Drug Could Help to Thwart Lymph Node Tumors’ Evasive Tactics

    Research by scientists at Massachusetts General Hospital (MGH) and Boston University School of Medicine may help to explain why cancer...
    Gut Microbiome Affected by Genetics More Than Once Thought
    • Jul 14, 2021

    Gut Microbiome Affected by Genetics More Than Once Thought

    Our gut microbiome is primarily affected by our lifestyle, including what we eat or the medications we take, most studies show. But a new...
    Imbalances in Mouth Microflora May Indicate Developing Rheumatoid Arthritis
    • Jun 2, 2021

    Imbalances in Mouth Microflora May Indicate Developing Rheumatoid Arthritis

    Scientists report specific dissimilarities in mouth microbial compositions among patients with early rheumatoid arthritis (ERA) and those...
    Potential Strategy for Acute Myeloid Leukemia Therapy Identified
    • May 4, 2021

    Potential Strategy for Acute Myeloid Leukemia Therapy Identified

    The results from in vitro and in vivo studies suggest that targeting a pathway that is essential for the survival of certain types of...
    Effect of COVID-19 Antiviral Remdesivir Multiplied 10-Fold by Hepatitis C Drugs
    • Apr 29, 2021

    Effect of COVID-19 Antiviral Remdesivir Multiplied 10-Fold by Hepatitis C Drugs

    Remdesivir, the only antiviral drug approved in the United States for treating COVID-19 patients, is up to 10 times more effective when...
    Breast Cancer Metastases Supported by Bone Microenvironment
    • Apr 21, 2021

    Breast Cancer Metastases Supported by Bone Microenvironment

    The bones are the most common place where metastatic breast cancer cells tend to go. Common treatments for metastatic breast cancer in...
    Potential Blood Biomarker for TBI, and Mechanistic Link with Alzheimer’s Disease Identified
    • Apr 16, 2021

    Potential Blood Biomarker for TBI, and Mechanistic Link with Alzheimer’s Disease Identified

    Scientists headed by a team at the Harrington Discovery Institute have discovered a potential new approach to preventing brain nerve...
    Early-Stage Alzheimer’s Disease Model Developed in Rhesus Macaques
    • Apr 5, 2021

    Early-Stage Alzheimer’s Disease Model Developed in Rhesus Macaques

    Scientists at the California National Primate Research Center (CNPRC) at the University of California, Davis, say they have developed a...
    3D Lab Model Developed in Search for New Therapies for AMD
    • Apr 1, 2021

    3D Lab Model Developed in Search for New Therapies for AMD

    Age-related macular degeneration (AMD), which leads to a loss of central vision, is the most frequent cause of blindness in adults 50...
    Gut Microbiome May Provide Novel Therapies for Neurological Disorders
    • Mar 12, 2021

    Gut Microbiome May Provide Novel Therapies for Neurological Disorders

    Researchers at the Baylor College of Medicine report that they have found that microbes in the gut may contribute to certain symptoms...
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