• Otávio Santiago

IDT Biologika and Exothera Collaborate on Scaling Up Viral Vaccines

IDT Biologika, a Germany-based CDMO specializing in vaccines, gene and immune therapy, and oncolytic viruses, and Exothera, a CDMO in Belgium, agreed to collaborate on the development of a large-scale manufacturing process for viral vector-based vaccines. The feasibility study is focussing on Modified Vaccinia Ankara (MVA) virus as a first example for IDT’s range of vector technologies.

Exothera reports that it has successfully transferred IDT Biologika’s upstream process from small- to large-scale using the NevoLine™ upstream platform developed by Univercells Technologies. The NevoLine system incorporates the scale-X™ structured fixed-bed bioreactor system, which offers a range of options to scale viral production from R&D to commercialization, according to Exothera.

The collaboration between IDT and Exothera is designed to demonstrate the application and increased performance of the NevoLine platform at full commercial capacity.

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